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Timeliness of childhood vaccination in England: A population-based cohort study
We described vaccine uptake for representative antigens (pertussis, pneumococcus, measles) by age in days and stratified by ethnicity, region and birth cohort. Alluvial diagrams were used to illustrate common journeys through the vaccination schedule, and we applied survival analysis using accelerated failure time models (AFT) to predict age of vaccine receipt based on timing of previous doses.RESULTS: 573,015 children were followed up until their fifth birthday, when they had 90.16 % coverage for two doses of measles, mumps, rubella (MMR) vaccine and 88.78% coverage for four doses of diphtheria, tetanus, pertussis (DTP) v...
Source: Vaccine - August 13, 2023 Category: Allergy & Immunology Authors: Anne M Suffel Jemma L Walker Elizabeth Williamson Helen I McDonald Charlotte Warren-Gash Source Type: research

Effectiveness and durability of BNT162b2 vaccine against hospital and emergency department admissions due to SARS-CoV-2 omicron sub-lineages BA.1 and BA.2 in a large health system in the USA: a test-negative, case-control study
This study is registered at ClinicalTrials.gov, NCT04848584, and is ongoing.FINDINGS: Of 65 813 total admissions during the study period, we included 16 994 in our analyses, of which 7435 were due to BA.1, 1056 were due to BA.2, and 8503 were not due to SARS-CoV-2. In adjusted analyses, two-dose vaccine effectiveness was 40% (95% CI 27 to 50) for hospitalisation and 29% (18 to 38) for emergency department admission against BA.1 and 56% (31 to 72) for hospitalisation and 16% (-5 to 33) for emergency department admission against BA.2. Three-dose vaccine effectiveness was 79% (74 to 83) for hospitalisation and 72% (67 to 77) ...
Source: Respiratory Care - October 10, 2022 Category: Respiratory Medicine Authors: Sara Y Tartof Jeff M Slezak Laura Puzniak Vennis Hong Timothy B Frankland Fagen Xie Bradley K Ackerson Srinivas R Valluri Luis Jodar John M McLaughlin Source Type: research

Primary Care Professionals' Attitudes Towards Vaccination Recommendation for Patients With Inflammatory Bowel Disease
CONCLUSIONS: There is room for improvement of vaccination recommendations by PCPs. Promoting continuing education and use of clinical tools may help support PCP immunization practices for patients with IBD.PMID:35779060 | DOI:10.1093/ibd/izac129
Source: Herpes - July 2, 2022 Category: Infectious Diseases Authors: Fang Xu Neal deJong Michael D Kappelman Kurt J Greenlund Susan A Carlson Source Type: research

Comparative Safety of BNT162b2 and mRNA-1273 Vaccines in a Nationwide Cohort of US Veterans
CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that there were few differences in risk of adverse events within 14 days of the first dose of either the BNT162b2 or the mRNA-1273 vaccine and small-magnitude differences within 42 days of the first dose. The 38-week risks of adverse events were low in both vaccine groups, although risks were lower for recipients of the mRNA-1273 vaccine than for recipients of the BNT162b2 vaccine. Although the primary analysis was designed to detect safety events unrelated to SARS-CoV-2 infection, the possibility that these differences may partially be explained by a low...
Source: Herpes - June 13, 2022 Category: Infectious Diseases Authors: Barbra A Dickerman Arin L Madenci Hanna Gerlovin Katherine E Kurgansky Jessica K Wise Michael J Figueroa Mu ñiz Brian R Ferolito David R Gagnon J Michael Gaziano Kelly Cho Juan P Casas Miguel A Hern án Source Type: research

Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Exploring electronic health records to estimate the extent of catch-up immunisation and factors associated with under-immunisation among refugees and asylum seekers in south east Queensland
CONCLUSION: This study indicates that the broader group of immigrants, and in particular refugees and asylum seekers, do not represent a homogenous group in terms of immunisation coverage, and that each cohort should be carefully considered during immunisation interventions and strategies. This will be particularly important during targeted health promotions and future immunisation programs in this cohort.PMID:34556368 | DOI:10.1016/j.vaccine.2021.09.026
Source: Vaccine - September 24, 2021 Category: Allergy & Immunology Authors: Mercy Moraa Nyanchoga Patricia Lee Gaery Barbery Source Type: research

DrugWAS: Drug-wide association studies for COVID-19 drug repurposing
In conclusion, this cohort study leveraged EHR data to identify a list of drugs that could be repurposed to improve COVID-19 outcomes. Further randomized clinical trials are needed to investigate the efficacy of the proposed drugs.PMID:34314511 | DOI:10.1002/cpt.2376
Source: Clinical Pharmacology and Therapeutics - July 27, 2021 Category: Drugs & Pharmacology Authors: Cosmin A Bejan Katherine N Cahill Patrick J Staso Leena Choi Josh F Peterson Elizabeth J Phillips Source Type: research

The impact of childhood pneumococcal conjugate vaccine immunisation on all-cause pneumonia admissions in Hong Kong: A 14-year population-based interrupted time series analysis
Vaccine. 2021 Apr 12:S0264-410X(21)00406-0. doi: 10.1016/j.vaccine.2021.03.090. Online ahead of print.ABSTRACTBACKGROUND: Nine years after the introduction of pneumococcal conjugate vaccine (PCV) in the United States, Hong Kong (HK) introduced the vaccine to its universal childhood immunisation programme in 2009. We aimed to assess the impact of childhood PCV immunisation on all-cause pneumonia (ACP) admissions among the overall population of HK.METHODS: In this population-based interrupted time series analysis, we used territory-wide population-representative electronic health records in HK to evaluate the vaccine impact....
Source: Vaccine - April 16, 2021 Category: Allergy & Immunology Authors: Qiuyan Yu Xue Li Min Fan Hong Qiu Angel Y S Wong Linwei Tian Celine S L Chui Philip H Li Lauren K W Lau Esther W Chan William B Goggins Patrick Ip Terry Y Lum Ivan F N Hung Benjamin J Cowling Ian C K Wong Mark Jit Source Type: research

The impact of the implementation of a clinical decision support system on the quality of healthcare services in a primary care setting
DISCUSSION: The electronic health record with CDS led to significantly improved uptake of immunizations and screening tests, with earlier diagnoses of breast and colon cancer. Evidence of improvement in chronic disease outcomes is still lacking.PMID:33681044 | PMC:PMC7928113 | DOI:10.4103/jfmpc.jfmpc_1728_20
Source: Primary Care - March 8, 2021 Category: Primary Care Authors: Ahmed Sherif Mahmoud Abdullah Alkhenizan Mohammed Shafiq Suad Alsoghayer Source Type: research

Communicating Benefits from Vaccines Beyond Preventing Infectious Diseases
AbstractDespite immunisation being one of the greatest medical success stories of the twentieth century, there is a growing lack of confidence in some vaccines. Improving communication about the direct benefits of vaccination as well as its benefits beyond preventing infectious diseases may help regain this lost confidence. A conference was organised at the Fondation Merieux in France to discuss what benefits could be communicated and how innovative digital initiatives can used for communication. During this meeting, a wide range of indirect benefits of vaccination were discussed. For example, influenza vaccination can red...
Source: Infectious Diseases and Therapy - June 23, 2020 Category: Infectious Diseases Source Type: research